If you have problem login to Drupal after some configuration changes or update, you can try the following steps:
- Try login using different browser, if you can login using another browser, likely a cookie problem.
- Clear the problem browser cookie of your site
- Try login again
If the above does not work, you can try edit sites/yoursite/settings.php
- specify the $base_url
- OR this fix to comment out the cookie section
Happy drupal-ing 
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