nice3z

Dr. Nadeau has a series of articles that could help you improve the performance of your Drupal install base. To be fair, performance boost using compression and caching on Apache & MySQL should work for other CMS and web content as well.

Don't miss the Do & Don't of

• Essential steps to speed up a Drupal web site
• Speed up a Drupal web site by enabling CSS file aggregation
• Speed up a Drupal web site by enabling MySQL query caching
• Speed up a Drupal web site by enabling page caching
• Speed up a Drupal web site by enabling PHP accelerator script caching
• Speed up a Drupal web site by using a simpler theme
• Speed up a web site by enabling Apache file compression
• Don’t use HTML white-space removal to speed up a web site

Out of those, the most significant improvement can be seen from Apache file compression. Don't bother with white space removal.